Dental avulsion is considered as one of the most severe types of traumatic tooth injuries because it causes damage to several structures and results in the complete displacement of the tooth from its socket in the alveolar bone. The ideal situation is to replant the tooth immediately after avulsion because the extra oral time is an important determinant for the success of the treatment and for a good prognosis. The aim of this systematic review was to identify the recommended natural storage m to store and transport avulsed tooth based on the survival capacity of periodontal ligament cells.This paper reviews the different storage media that have been evaluated for avulsed teeth based on full-length research papers retrieved from PubMed/Medline, Lilacs, BBO and SciELO electronic databases using the key words ‘storage medium’, ‘avulsion’, ‘tooth avulsion’, ‘replantation’, ‘tooth replantation’, ‘milk’ and ‘propolis’. Based on the application of inclusion and exclusion criteria, About 14 papers have been selected and critically reviewed with respect to the characteristics, efficacy and ease of access of the storage media. The review of this study shows and includes a wide array of wet storage media that have been evaluated in laboratory-based studies on PDL cells found on adult permanent teeth. Among the natural products other than milk, propolis, coconut water, green tea extract, egg white, green tea extract, Alovera gel, pomegranate juice, salvia officinalis followed by dragon blood sap (Croton Lechleri)  were recommended based on the cell viability and its longevity. In an emergency, it is important for dentists to consider the circumstances of the accident, the location and suggest an appropriate transport media.