E-viri
Recenzirano
Odprti dostop
-
Gadegbeku, Crystal A.; Gipson, Debbie S.; Holzman, Lawrence B.; Ojo, Akinlolu O.; Song, Peter X.K.; Barisoni, Laura; Sampson, Matthew G.; Kopp, Jeffrey B.; Lemley, Kevin V.; Nelson, Peter J.; Lienczewski, Chrysta C.; Adler, Sharon G.; Appel, Gerald B.; Cattran, Daniel C.; Choi, Michael J.; Contreras, Gabriel; Dell, Katherine M.; Fervenza, Fernando C.; Gibson, Keisha L.; Greenbaum, Larry A.; Hernandez, Joel D.; Hewitt, Stephen M.; Hingorani, Sangeeta R.; Hladunewich, Michelle; Hogan, Marie C.; Hogan, Susan L.; Kaskel, Frederick J.; Lieske, John C.; Meyers, Kevin E.C.; Nachman, Patrick H.; Nast, Cynthia C.; Neu, Alicia M.; Reich, Heather N.; Sedor, John R.; Sethna, Christine B.; Trachtman, Howard; Tuttle, Katherine R.; Zhdanova, Olga; Zilleruelo, Gastòn E.; Kretzler, Matthias
Kidney international, 04/2013, Letnik: 83, Številka: 4Journal Article
The Nephrotic Syndrome Study Network (NEPTUNE) is a North American multicenter collaborative consortium established to develop a translational research infrastructure for nephrotic syndrome. This includes a longitudinal observational cohort study, a pilot and ancillary study program, a training program, and a patient contact registry. NEPTUNE will enroll 450 adults and children with minimal change disease, focal segmental glomerulosclerosis, and membranous nephropathy for detailed clinical, histopathological, and molecular phenotyping at the time of clinically indicated renal biopsy. Initial visits will include an extensive clinical history, physical examination, collection of urine, blood and renal tissue samples, and assessments of quality of life and patient-reported outcomes. Follow-up history, physical measures, urine and blood samples, and questionnaires will be obtained every 4 months in the first year and biannually, thereafter. Molecular profiles and gene expression data will be linked to phenotypic, genetic, and digitalized histological data for comprehensive analyses using systems biology approaches. Analytical strategies were designed to transform descriptive information to mechanistic disease classification for nephrotic syndrome and to identify clinical, histological, and genomic disease predictors. Thus, understanding the complexity of the disease pathogenesis will guide further investigation for targeted therapeutic strategies.
Avtor
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.