E-viri
Recenzirano
Odprti dostop
-
Branton, Daniel; Deamer, David W; Marziali, Andre; Bayley, Hagan; Benner, Steven A; Butler, Thomas; Di Ventra, Massimiliano; Garaj, Slaven; Hibbs, Andrew; Huang, Xiaohua; Jovanovich, Stevan B; Krstic, Predrag S; Lindsay, Stuart; Ling, Xinsheng Sean; Mastrangelo, Carlos H; Meller, Amit; Oliver, John S; Pershin, Yuriy V; Ramsey, J Michael; Riehn, Robert; Soni, Gautam V; Tabard-Cossa, Vincent; Wanunu, Meni; Wiggin, Matthew; Schloss, Jeffery A
Nature biotechnology, 10/2008, Letnik: 26, Številka: 10Journal Article
A nanopore-based device provides single-molecule detection and analytical capabilities that are achieved by electrophoretically driving molecules in solution through a nano-scale pore. The nanopore provides a highly confined space within which single nucleic acid polymers can be analyzed at high throughput by one of a variety of means, and the perfect processivity that can be enforced in a narrow pore ensures that the native order of the nucleobases in a polynucleotide is reflected in the sequence of signals that is detected. Kilobase length polymers (single-stranded genomic DNA or RNA) or small molecules (e.g., nucleosides) can be identified and characterized without amplification or labeling, a unique analytical capability that makes inexpensive, rapid DNA sequencing a possibility. Further research and development to overcome current challenges to nanopore identification of each successive nucleotide in a DNA strand offers the prospect of 'third generation' instruments that will sequence a diploid mammalian genome for approximately $1,000 in approximately 24 h.
Avtor
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.