E-viri
Recenzirano
-
Kiemeney, Lambertus A; Witjes, J Alfred; Stefansson, Kari; Tryggvadottir, Laufey; Stefansson, Hreinn; Heijer, Martin den; Swinkels, Dorine W; Ingason, Andres; Thorsteinsdottir, Unnur; Becker, Diane M; Thorlacius, Steinunn; Jorgensen, Torben; Walters, G Bragi; Zusmanovich, Pasha; Olafsdottir, Gudridur H; Yanek, Lisa R; Verbeek, Andre L M; Hansen, Torben; Becker, Lewis C; Pedersen, Oluf; Gudbjartsson, Daniel F; Borch-Johnsen, Knut; Steinberg, Stacy; Rafnar, Thorunn; Gylfason, Arnaldur; Helgadottir, Anna; Gulcher, Jeffrey; Thorleifsson, Gudmar; Franke, Barbara; Kong, Augustine; Aben, Katja K; Jonsson, Thorvaldur; Andersen, Gitte; Halldorsson, Bjarni V; Sulem, Patrick; Steinthorsdottir, Valgerdur; Olafsdottir, Elinborg J
Nature genetics, 05/2008, Letnik: 40, Številka: 5Journal Article
Adult human height is one of the classical complex human traits. We searched for sequence variants that affect height by scanning the genomes of 25,174 Icelanders, 2,876 Dutch, 1,770 European Americans and 1,148 African Americans. We then combined these results with previously published results from the Diabetes Genetics Initiative on 3,024 Scandinavians and tested a selected subset of SNPs in 5,517 Danes. We identified 27 regions of the genome with one or more sequence variants showing significant association with height. The estimated effects per allele of these variants ranged between 0.3 and 0.6 cm and, taken together, they explain around 3.7% of the population variation in height. The genes neighboring the identified loci cluster in biological processes related to skeletal development and mitosis. Association to three previously reported loci are replicated in our analyses, and the strongest association was with SNPs in the ZBTB38 gene.
Avtor
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.