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de Bresser, Carolijn J M; Petri, Bart-Jeroen; Braat, Arthur J A T; de Keizer, Bart; van Treijen, Mark J C; Dankbaar, Jan Willem; Pameijer, Frank A; Kok, Marius G J; de Ridder, Mischa; van Nesselrooij, Bernadette P M; de Bree, Remco; de Borst, Gert J; Rijken, Johannes A
Cancers, 02/2024, Letnik: 16, Številka: 5Journal Article
The Dutch guideline for patients suspected of head and neck paragangliomas (HNPGLs) recommends magnetic resonance imaging (MRI) and/or computed tomography (CT) of the head and neck area. Additionally, it suggests considering additional nuclear imaging. The aim of this study was to evaluate the outcomes of GaGa-DOTATOC PET/CT compared to MRI in patients with suspected HNPGLs and carriers of genetic variations. In this single-center pilot study, retrospective data were obtained from consecutive patients between 2016 and 2023. Both MRI and GaGa-DOTATOC PET/CT were performed within 12 months. The primary outcome was the location of HNPGLs. A total of 25 consecutive patients were included, and 7 patients (28.0%, = 0.5) showed differences between the imaging modalities, of whom 5 patients had unexpected localizations with additional uptake by somatostatin receptors (SSTR) on the GaGa-DOTATOC PET/CT. The authors recommend performing baseline imaging with GaGa-DOTATOC PET/CT (if available) in variant carriers and using MRI/CT for follow-up according to the regional protocol, thereby shifting the gold standard for baseline imaging from MRI/CT to GaGa-DOTATOC PET/CT.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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