E-viri
Recenzirano
Odprti dostop
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Gomberg-Maitland, Mardi, MD, MSc; Bull, Todd M., MD; Saggar, Rajeev, MD; Barst, Robyn J., MD; Elgazayerly, Amany, MD, PhD; Fleming, Thomas R., PhD; Grimminger, Friedrich, MD, PhD; Rainisio, Maurizio, PhD; Stewart, Duncan J., MD; Stockbridge, Norman, MD, PhD; Ventura, Carlo, MD, PhD; Ghofrani, Ardeschir H., MD; Rubin, Lewis J., MD
Journal of the American College of Cardiology, 12/2013, Letnik: 62, Številka: 25Journal Article, Conference Proceeding
A greater understanding of the epidemiology, pathogenesis, and pathophysiology of pulmonary artery hypertension (PAH) has led to significant advances, but the disease remains fatal. Treatment options are neither universally available nor always effective, underscoring the need for development of novel therapies and therapeutic strategies. Clinical trials to date have provided evidence of efficacy, but were limited in evaluating the scope and duration of treatment effects. Numerous potential targets in varied stages of drug development exist, in addition to novel uses of familiar therapies. The pursuit of gene and cell-based therapy continues, and device use to help acute deterioration and chronic management is emerging. This rapid surge of drug development has led to multicenter pivotal clinical trials and has resulted in novel ethical and global clinical trial concerns. This paper will provide an overview of the opportunities and challenges that await the development of novel treatments for PAH.
Avtor
Vnos na polico
Trajna povezava
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Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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