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Lee, Chun-Ting; Huang, Keng-Shiang; Shaw, Jei-Fu; Chen, Jung-Ren; Kuo, Wen-Shuo; Shen, Gangxu; Grumezescu, Alexandru Mihai; Holban, Alina Maria; Wang, Yi-Ting; Wang, Jun-Sheng; Hsiang, Yi-Ping; Lin, Yu-Mei; Hsu, Hsiao-Han; Yang, Chih-Hui
Frontiers in pharmacology, 11/2020, Letnik: 11Journal Article
( ) is a fungus with a long history of widespread use in folk medicine, and its biological and medicinal functions are well studied. A crucial pharmacological effect of is immunomodulation. In this review, we catalog the immunomodulatory effects of different extracts of , namely total extracts, polysaccharides and cordycepin Total extracts obtained using water or 50% ethyl alcohol and polysaccharides from were discovered to tend to promote type 1 immunity, whereas total extracts obtained using 70-80% ethyl alcohol and cordycepin from were more likely to promote type 2 immunity. This article is the first to classify the immunomodulatory effects of different extracts of . In addition, we discovered a relationship between different segments or extracts and differing types of immunity. This review can provide the readers a comprehensive understanding on the immunomodulatory effects of the precious folk medicine and guidance on its use for both health people and those with an immunodeficiency.
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in: SICRIS
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