Abstract The Pan-STARRS1 (PS1) Science Consortium has carried out a set of imaging surveys using the 1.4 gigapixel GPC1 camera on the PS1 telescope. As this camera is composed of many individual electronic readouts and covers a very large field of view, great care was taken to ensure that the many instrumental effects were corrected to produce the most uniform detector response possible. We present the image-detrending steps used as part of the processing of the data contained within the public release of Pan-STARRS1 Data Release 1 (DR1). In addition to the single image processing, the methods used to transform the 375,573 individual exposures into a common sky-oriented grid are discussed, as well as those used to produce both the image stack and difference combination products.