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Live oral typhoid vaccineSalmonellaTyphi Ty21a - A surrogate vaccine against non-typhoid salmonella?Kantele, Anu; Pakkanen, Sari H; Siitonen, Anja; Karttunen, Riitta; Kantele, Jussi M
Vaccine, 11/2012, Letnik: 30, Številka: 50Journal Article
Highlights * There are no vaccines available against non-typhoid Salmonella (NTS). * Intestinal antibodies against O-antigens have proven protective in animal studies. * Oral typhoid vaccine Ty21a effectively elicits intestinal antibodies to O-antigens. * These antibodies cross-react with common NTS strains, such asSalmonellaEnteritidis. * Ty21a may have cross-protective efficacy against numerous NTS strains.
