A large number of diseases occur primarily due to lack of oxygen in the tissue and because of accumulation of toxins in the body. Painless an natural treatment with ozone helps with postoperating recovery, and can cure many diseases and injuries, and even tumors, and is now commonly used in dentistry. Ozone has a positive effect on wound healing, stimulation of the immune system, circulation and tissue oxygenation and on reduction of swelling and pain. Clinical studies of ozone have led to the conclusion that, ozone in the treatment of inflammatory gynecological diseases has basically the antioxidant effect, while also serving as a fixer of cellular and humoral immunity. Ozone in the treatment of such conditions has detoxicating, analgetic and sedative effects, what leads to a reduction of standard drugs used in these situations. Except in gynecology, ozone has applications in other fields of medicine: it improves blood circulation and supply of blood cells and tissue with oxygen, it helps with many diseases and malignant neoplasms in their foundations.