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Gräf, Tiago; Vazquez, Cynthia; Giovanetti, Marta; de Bruycker-Nogueira, Fernanda; Fonseca, Vagner; Claro, Ingra Morales; de Jesus, Jaqueline Goes; Gómez, Andrea; Xavier, Joilson; de Mendonça, Marcos Cesar Lima; Villalba, Shirley; Torales, Juan; Gamarra, Maria Liz; Thézé, Julien; de Filippis, Ana Maria Bispo; Azevedo, Vasco; de Oliveira, Tulio; Franco, Leticia; de Albuquerque, Carlos F Campelo; Irala, Sandra; Holmes, Edward Charles; Méndez Rico, Jairo Andrés; Alcantara, Luiz Carlos Junior
Emerging infectious diseases 27, Številka: 5Journal Article
Paraguay has been severely affected by emergent Zika and chikungunya viruses, and dengue virus is endemic. To learn more about the origins of genetic diversity and epidemiologic history of these viruses in Paraguay, we deployed portable sequencing technologies to strengthen genomic surveillance and determine the evolutionary and epidemic history of arthropod-borne viruses (arboviruses). Samples stored at the Paraguay National Central Laboratory were sequenced and subjected to phylogenetic analysis. Among 33 virus genomes generated, we identified 2 genotypes of chikungunya and 2 serotypes of dengue virus that circulated in Paraguay during 2014-2018; the main source of these virus lineages was estimated to be Brazil. The evolutionary history inferred by our analyses precisely matched the available travel history of the patients. The genomic surveillance approach used was valuable for describing the epidemiologic history of arboviruses and can be used to determine the origins and evolution of future arbovirus outbreaks.
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Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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