Display omitted •Valorization of agro-industrial wastes has been comprehensively discussed.•Agro-industrial wastes are potential source for value creation.•Methodologies for obtaining products from agro-industrial wastes have been appraised.•Applications of LCA in agro-industrial circular bioeconomy have been uncovered. Energy recovery from waste resources is a promising approach towards environmental consequences. In the prospect of environmental sustainability, utilization of agro-industrial waste residues as feedstock for biorefinery processes have gained widespread attention. In the agro-industry, various biomasses are exposed to different unit processes for offering value to various agro-industrial waste materials. Agro-industrial wastes can generate a substantial amount of valuable products such as fuels, chemicals, energy, electricity, and by-products. This paper reviews the methodologies for valorization of agro-industrial wastes and their exploitation for generation of renewable energy products. In addition, management of agro-industrial wastes and products from agro-industrial wastes have been elaborated. The waste biorefinery process using agro-industrial wastes does not only offer energy, it also offers environmentally sustainable modes, which address effective management of waste streams. This review aims to highlight the cascading use of biomass from agro-industrial wastes into the systemic approach for economic development.