E-viri
Recenzirano
Odprti dostop
-
Garcia, Aurora; Yáñez, Aina M.; Bennasar-Veny, Miquel; Navarro, Capilla; Salva, Joan; Ibarra, Olga; Gomez-Juanes, Rocío; Serrano-Ripoll, María J.; Oliván, Bárbara; Gili, Margalida; Roca, Miquel; Riera-Serra, Pau; Aguilar-Latorre, Alejandra; Montero-Marin, Jesús; Garcia-Toro, Mauro
Psychiatry research, January 2023, 2023-01-00, 20230101, Letnik: 319Journal Article
•Therapies for treatment-resistant depression need to be improved.•Lifestyle modification might be effective against treatment-resistant depression.•Insufficient patient recruitment probably prevented confirmation in this study.•Our program improved life quality and decreased use of antidepressants.•The COVID-19 pandemic made it difficult to perform more thorough evaluations. The high prevalence of depression is partly attributable to the poor response of patients to first-line antidepressants. Multimodal programs that promote a healthy lifestyle are successful in treating depression when used as a complementary therapy, but their medium- and long-term benefits have not been demonstrated for patients with treatment-resistant depression (TRD). The main aim of this study was to compare the effectiveness of a lifestyle modification program (LMP) with mindfulness-based cognitive therapy (MBCT) and a placebo-control (written suggestions for lifestyle changes) in Spanish patients with TRD. This controlled clinical trial randomized 94 patients with TRD into 3 arms. The primary outcome was the Beck Depression Inventory-II (BDI-II) score at baseline, 2, 6 and 12 months. The secondary outcomes were changes in scores that evaluated quality-of-life, adherence to the Mediterranean diet, physical activity, and social support. Relative to the placebo group, the LMP and MBCT groups had significantly better quality of life (p = 0.017; p = 0.027), and the LMP group had significantly better adherence to the Mediterranean diet (p<0.001) and reduced use of antidepressants (p = 0.036). However, the three groups showed no significant differences in BDI-II score. Only about half of the planned 180 patients were recruited, in part due to the COVID-19 pandemic. There was no evidence that the LMP treatment significantly reduced symptoms of depression relative to the other groups during the COVID-19 lockdown.
Avtor
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.