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Cuzon, G; Naas, T; Bogaerts, P; Glupczynski, Y; Nordmann, P
Diagnostic microbiology and infectious disease, 08/2013, Letnik: 76, Številka: 4Journal Article
Abstract The Check-MDR Carba test (Check-Points, Wageningen, Netherlands), which is based on specific molecular recognition of blaNDM , blaKPC , blaOXA-48 , blaVIM , and blaIMP genes by DNA probe ligation and real-time PCR detection, was evaluated on 183 well-characterized Gram-negative rods. Representatives of the 5 gene families were accurately identified (specificities and sensitivities of 100%) within 4.5 hours. This test may be helpful to differentiate carbapenem resistance mediated by carbapenemases from those involving other mechanisms.
