Levels of 17 polychlorinated biphenyl congeners (PCBs) and seven organochlorine pesticides (OCPs) were measured in the muscle tissue of 18 commercially important fish species from the eastern Adriatic Sea. PCBs <LOD-8,866 ng g-1 lipid weight (lw) accounted for over 66 % of all analysed compounds. Their pattern was dominated by PCB-138 and PCB-153. DDE (14.2-649 ng g-1 lw) was the prevalent DDT isomer in all samples, suggesting no recent DDT input. β-, γ- and α-HCH and HCB were found in less than 50 % of samples. The analysed organic contaminants did not seem to bioaccumulate up the food web (trophic levels 3.0 to 4.5). Our findings show no risk of chronic (non-cancerous) effects on human health Maseni udjeli 17 poliklorbifenila (PCB) i 7 organoklorovih pesticida (OCP) izmjereni su u mišićnom tkivu 18 komercijalno važnih ribljih vrsta iz istočnog Jadranskog mora. Maseni udjeli PCB-a (<LOD do 8.866 ng g-1 masti) činili su više od 66 % svih analiziranih spojeva. U njihovu profilu PCB-138 i PCB-153 dominantni su kongeneri. DDE (14,2-649 ng g-1 masti), glavni izomer DDT-a, jedini je detektiran u svim uzorcima. U manje od 50 % analiziranih uzoraka nađeni su β-, γ- i α-HCH te HCB. U rasponu trofičkih razina analiziranih vrsta (3,0-4,5) nije bilo bioakumulacije organskih zagađivala u hranidbenom lancu. Rezultati procjene rizika za ljudsko zdravlje pokazali su da nema rizika od kroničnih (nekancerogenih) utjecaja na ljudsko zdravlje.