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van Vliet, Elvira O.G., BSc; de Kieviet, Jorrit F., MSc; van der Voorn, J. Patrick, MD, PhD; Been, Jasper V., MD, MPH, PhD; Oosterlaan, Jaap, PhD; van Elburg, Ruurd M., MD, PhD
American journal of obstetrics and gynecology, 06/2012, Letnik: 206, Številka: 6Journal Article
Objective The objective of the study was to compare neonatal morbidity and long-term neurodevelopmental outcome between very preterm infants with placental underperfusion and very preterm infants with histological chorioamnionitis. Study Design We measured the mental and motor development at age 2 and 7 years in 51 very preterm infants with placental underperfusion and 21 very preterm infants with histological chorioamnionitis. Results At 2 years, very preterm infants with placental underperfusion had poorer mental development than very preterm infants with histological chorioamnionitis (mean SD 90.8 18.3 vs 104.1 17.2, adjusted d = 1.12, P = .001). Motor development was not different between both groups (92.8 17.2 vs 96.8 8.7, adjusted d = 0.52, P = .12). At 7 years, large, although nonsignificant, effects were found for better mental and motor development and fewer behavioral problems in infants with histological chorioamnionitis. Conclusion Placental pathology contributes to variance in mental development at 2 years and should be taken into account when evaluating neurodevelopmental outcome of very preterm infants.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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