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Littlejohns, Thomas J; Holliday, Jo; Gibson, Lorna M; Garratt, Steve; Oesingmann, Niels; Alfaro-Almagro, Fidel; Bell, Jimmy D; Boultwood, Chris; Collins, Rory; Conroy, Megan C; Crabtree, Nicola; Doherty, Nicola; Frangi, Alejandro F; Harvey, Nicholas C; Leeson, Paul; Miller, Karla L; Neubauer, Stefan; Petersen, Steffen E; Sellors, Jonathan; Sheard, Simon; Smith, Stephen M; Sudlow, Cathie L M; Matthews, Paul M; Allen, Naomi E
Nature communications, 05/2020, Letnik: 11, Številka: 1Journal Article
UK Biobank is a population-based cohort of half a million participants aged 40-69 years recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi-modal imaging study, with the aim of re-inviting 100,000 participants to undergo brain, cardiac and abdominal magnetic resonance imaging, dual-energy X-ray absorptiometry and carotid ultrasound. The combination of large-scale multi-modal imaging with extensive phenotypic and genetic data offers an unprecedented resource for scientists to conduct health-related research. This article provides an in-depth overview of the imaging enhancement, including the data collected, how it is managed and processed, and future directions.
