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Claure-Del Granado, Rolando; Acker, Andrew; Aisa, Tharwat; Alex, Beatrice; Cabrita, Joana Alves; Atif, Minahel; Bak, Erica; Bani-Sadr, Firouzé; Benech, Nicolas; Bitker, Laurent; Borges, Diogo; Bouziotis, Jason; Monteiro, Filipa Brás; Bugaeva, Polina; Casimiro, José; Cavayas, Alexandros; Chan, Adrienne; Cheng, Matthew Pellan; Chua, Hiu Jian; Collins, Michael; Connor, Marie; Cornet, Alexander Daniel; Corpuz, Arianne Joy; Couffin-Cadiergues, Sandrine; Cruz Bermúdez, Juan Luis; Curran, Colleen; Freitas de Oliveira França, Rafael; Donohue, Yoann; Dudman, Susanne; Duthoit, Juliette; Dyrhol-Riise, Anne Margarita; Eloy, Philippine; Enderle, Isabelle; Etienne, Manuel; Gagliardi, Massimo; Gilroy, Elaine; Goh, Jin Yi; Guellec, Dewi; Hammond, Naomi; Hardwick, Hayley; Hiraiwa, Hiroaki; Ho, Yi Bin; Ming-Yang Hsu, Jimmy; Ing, Yun Sii; Jaafar, Danielle; Jelani, Anilawati Mat; Kaleesvran, Thavamany; Khan, Coralie; Kho, Michelle E.; Kiiza, Peter; Granerud, Beathe Kiland; Le Bihan, Clément; Le Maréchal, Marion; Lee, Jennifer; Lefebvre, Bénédicte; Leone, Michela; Lesouhaitier, Mathieu; Lester-Grant, Amy; Louis, Guillame; Lowik, Marije; Luque, Nestor; Machado, Moïse; Mankikian, Julie; Sant`Ana Malaque, Ceila Maria; Martynenko, Olga; McElroy, Aine; McNicholas, Bairbre; Mele, Ferruccio; Meysonnier, Vanina; Misnan, Nor Arisah; Cely, Lina Morales; O'Shea, Linda; Ouamara, Nadia; Panda, Prasan Kumar; Paxton, William A.; Jiménez, Miguel Pedrera; Periel, Luis; Prapa, Sofia; Rasmin, Menaldi; Roberts, Stephanie; Robineau, Olivier; Roriz, Mélanie; Russell, Clark D.; Ryan, Maeve; Santos, Marlene; Balazote, Pablo Serrano; Shi, Haixia; Silva, Maria Joao; Sousa, Marta; Sousa, Ana Chora; Stabler, Sarah; Suppiah, Deepashankari; Tawfik, Hassan; Mohd Thabit, Alif Adlan; Tissot, Noémie; Tonby, Kristian; Udy, Andrew; Vencken, Sebastian; Whelan, Bryan; Willems, Sue
Kidney international reports, 08/2023, Letnik: 8, Številka: 8Journal Article
Acute kidney injury (AKI) has been identified as one of the most common and significant problems in hospitalized patients with COVID-19. However, studies examining the relationship between COVID-19 and AKI in low- and low-middle income countries (LLMIC) are lacking. Given that AKI is known to carry a higher mortality rate in these countries, it is important to understand differences in this population. This prospective, observational study examines the AKI incidence and characteristics of 32,210 patients with COVID-19 from 49 countries across all income levels who were admitted to an intensive care unit during their hospital stay. Among patients with COVID-19 admitted to the intensive care unit, AKI incidence was highest in patients in LLMIC, followed by patients in upper-middle income countries (UMIC) and high-income countries (HIC) (53%, 38%, and 30%, respectively), whereas dialysis rates were lowest among patients with AKI from LLMIC and highest among those from HIC (27% vs. 45%). Patients with AKI in LLMIC had the largest proportion of community-acquired AKI (CA-AKI) and highest rate of in-hospital death (79% vs. 54% in HIC and 66% in UMIC). The association between AKI, being from LLMIC and in-hospital death persisted even after adjusting for disease severity. AKI is a particularly devastating complication of COVID-19 among patients from poorer nations where the gaps in accessibility and quality of healthcare delivery have a major impact on patient outcomes. Display omitted
