Food security, human health and well-being largely depend on biodiver-sity. Biodiversity supports agriculture through ecosystem services such as pollination and water purification, and provides access to natural medicines, which are the primary source of health care for 4 billion people worldwide.1 However, climate stressors exert signifi-cant pressure on terrestrial and marine ecosystems.1,2 Climate change causes increases to temperature and changes to precipitation patterns. Importantly, it will also cause changes to the frequency and intensity of extreme events globally.3Tropical cyclones, also known as typhoons or hurricanes,4 are among the most destructive natural hazards that threaten the nexus of food-health-bio-diversity. Between 1998 and 2017, tropi-cal cyclones killed 233 000 people and affected an estimated 726 million people worldwide.3 While recent analyses show that between 1990 and 2020 the annual number of tropical cyclones has declined, losses and damages have significantly in-creased, likely due to population growth and higher value of coastal assets.5 Be-cause of climate change, tropical cyclones are projected to become more powerful, with storm surges causing higher levels of inundation because of sea-level rise, as well as higher rates of associated precipi-tation (Box 1).6Tropical cyclones occur in areas where large concentrations of people and infra-structure exist - as well as poverty and inequalities that contribute to countries' vulnerability to climate risks. As biodi-versity is highest around the tropics,2 tropical cyclones and their associated hazards affect not only people and assets, but also species and ecosystems that sup-port livelihoods, services and products for billions of people. Hence, weather extremes such as tropical cyclones have important short- and long-term impacts on food security, health and nutrition, and biodiversity.However, much remains to be un-derstood about the range of ecological impacts of tropical cyclones; researchers and policy-makers need to give more importance to the role of biodiversity in food systems, health and nutrition.7,8 Here, we discuss how tropical cyclones affect the food-biodiversity-health nexus and highlight future research and policy opportunities.