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Mathias, Rasika A; Chavan, Sameer; Boorgula, Meher; Cookson, William O.C., MD, DPhil; Willis-Owen, Saffron; Rafaels, Nicholas M; Hanifin, Jon M., MD, FAAAAI; Paller, Amy; Schneider, Lynda C., MD, FAAAAI; Gallo, Richard, MD, PhD; Guttman-Yassky, Emma, MD, PhD; Ong, Peck Y., MD, FAAAAI; Ruczinski, Ingo; Beaty, Terri; Gao, Li; Beck, Lisa A., MD, FAAAAI; Moffat, Miriam; Leung, Donald Y.M., MD, PhD, FAAAAI; Barnes, Kathleen C., PhD, FAAAAI
Journal of allergy and clinical immunology, 02/2017, Letnik: 139, Številka: 2Journal Article
Methods We use whole genome sequencing on 493 European American AD subjects (average age = 26, average severity measured by EASI score = 14.5) and 237 non-atopic controls in the Atopic Dermatitis Research Network (ADRN) study to test for association with single nucleotide polymorphisms (SNPs) in the EDC as risk determinants of AD as well as severity of disease.
