The patients and staff safety is one of the healthcare quality standards listed by "The Rules on quality standards and the method of their application". The healthcare care law implies medical procedure safety with the main goal avoiding harmful adverse events. That fact obliges establishing system security by reporting, analyzing and preventing medical errors that can often cause unwanted incidents. By monitoring and analyzing the frequency of certain indicators we can obtain useful information on trends and possible ways to prevent such future events. One of the indicators of patient safety in hospital healthcare system is standardized mortality rate which is used in monitoring specific diagnosis. One of them being acute myocardial heart attack. Mortality rate of acute myocardial heart attack depends not only on the clinical process but also on some other factors that can also be present and affect it. According to the Organisation for Economic Co-operation and Development report, mortality rate for the patients with acute myocardial heart attack within 30 days of hospital admission is 10,8%, while in the Sestre milosrdnice University Hospital Center mortality rate in the year of 2015 was only 9 % which is a good outcome indicator for patient safety management in this hospital.