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Chen, J; Zhao, H.-B
Neuroscience, 04/2014, Letnik: 265Journal Article
Highlights • Kir4.1 ( KCNJ10 ) is required for EP and spiral ganglion function in the inner ear. • Deficiency of Kir4.1 causes deafness with EAST or SeSAME syndromes. • Deafness mutants show “loss of function” and can be rescued by WT isoform. • Deafness mechanisms of Kir4.1 deficiency are discussed and prospected.
