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Smernice za zdravljenje zastrupitev s paracetamolom = Guidelines for paracetamol poisoning treatmentŠarc, Lucija, 1968- ...Paracetamol overdose results in an accumulation of the reactive, hepatotoxic metabolite N-acetyl-p-benzoquinoneimin (NAPKQI) which can cause serious liver injury. Recognition of paracetamol overdose, ... hepatotoxicity risk estimation and early treatment are crutial in paracetamol poisoniong management. In ingestion of potential hepatotoxic dose of paracetamol decontamination and early treatment with N-acetylcysteine (NAC) are indicated. Both, 20-hours intravenous and 72-hurs oral regimes of NAC administration are successful. By antidote regime selection we should consider patient condition and time after paracetamol overdose. In severe hepatotoxicity, criteria for liver transplantation should be regularly evaluated and mechanisms for liver transplantation must be activated in time.Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 83, št. 3, mar. 2014, str. 201-208)Type of material - article, component part ; adult, seriousPublish date - 2014Language - slovenianCOBISS.SI-ID - 31311321
Author
Šarc, Lucija, 1968- |
Jamšek, Marija, 1950- |
Grenc, Damjan |
Brvar, Miran
Topics
paracetamol |
poisoning |
liver injury |
paracetamol |
zastrupitve |
jetrna odpoved
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source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 83, št. 3, mar. 2014, str. 201-208)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Šarc, Lucija, 1968- | 27888 |
Jamšek, Marija, 1950- | 01976 |
Grenc, Damjan | 37918 |
Brvar, Miran | 24927 |
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