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Comparison of rubella virus- and herpes virus-associated anterior uveitis : clinical manifestations and visual prognosisWensing, Barbara ...Purpose: To compare the clinical characteristics and visual prognosis of patients with anterior uveitis (AU) and intraocular fluid analysis positive for rubella virus (RV), herpes simplex virus ... (HSV), or varicella zoster virus (VZV). DESIGN: Retrospective, observational study. Participants: The study included 106 patients with AU and positive polymerase chain reaction (PCR) results, Goldmann-Witmer coefficients (GWCs), or both, for RV (n = 57), HSV (n= 39), or VZV (n = 10). Mezhods: Clinical records of the included patients were analyzed retrospectively; demographic constitution, ophthalmologic characteristics, and visual prognosis were compared. Main outcome measures: Age, gender, and diverse clinical and laboratory characteristics, including course and laterality of AU; prevalence of positive results for PCR, GWC, or both; conjunctival redness; corneal edema; history of keratitis; presence of keratic precipitates; synechiae; heterochromia; and grade of inflammation. In addition, complications and visual acuity at 1 and 3 years of follow-up were recorded. Results: All 3 types of viral AU were characterized by unilateral involvement (80%-97%). Rubella virus AU was characterized by younger age at onset and chronic course and typically was associated with cataract at presentation. Heterochromia was present in 23% of RV AU patients. Anterior uveitis associated with HSV or VZV occurred characteristically in older patients and frequently followed an acute course. Clinical features associatedwith herpetic AU included conjunctival redness, corneal edema, history of keratitis, and development of posterior synechiae. Herpes simplex virus AU often had severe anterior chamber inflammation, whereas the presence of vitritis was more common in RV AU and VZV AU. The prevalence of documented intraocular pressure (IOP) of more than 30 mmHg (25%-50%; P = 0.06) and development of glaucoma (18%-30%; P = 0.686) were similar in all 3Source: Ophthalmology. - ISSN 0161-6420 (Vol. 118, issue 10, 2011, str. 1905-1910)Type of material - article, component partPublish date - 2011Language - englishCOBISS.SI-ID - 29417433
Author
Wensing, Barbara |
Relvas, Lia M. |
Caspers, Laure E. |
Vidović Valentinčič, Nataša |
Štunf, Špela |
Groot-Mijnes, Jolanda D.F. de |
Rothova, Aniki
Topics
Adult |
Aged |
Aged, 80 And Over |
Aqueous Humor |
Virology |
Child |
Dna, Viral |
Analysis |
Eye Infections, Viral |
Diagnosis |
Physiopathology |
Virology |
Genome, Viral |
Genetics |
Herpes Simplex |
Physiopathology |
Diagnosis |
Virology |
Herpes Zoster Ophthalmicus |
Diagnosis |
Physiopathology |
Virology |
Herpesvirus 1, Human |
Genetics |
Isolation & Purification |
Herpesvirus 3, Human |
Genetics |
Isolation & Purification |
Intraocular Pressure |
Physiology |
Polymerase Chain Reaction |
Prognosis |
Retrospective Studies |
Rubella |
Physiopathology |
Diagnosis |
Virology |
Rubella Virus |
Genetics |
Isolation & Purification |
Uveitis, Anterior |
Diagnosis |
Physiopathology |
Virology |
Visual Acuity |
Physiology |
Herpes simpleks |
Polimerazna, verižna reakcija |
Uveitis prednji |
Otrok |
Starostniki |
Starost 80 in več |
Odrasli |
Prekatna vodica |
Očesne infekcije virusne |
Rdečke, virus |
Vid, ostrina |
Herpes zoster očesni |
Prognoza |
Retrospektivne študije |
Genom virusni |
Intraokularni pritisk |
Herpesvirus 3 človeški |
Rdečke |
DNA virusna |
Herpesvirus 1 človeški
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Wensing, Barbara | |
Relvas, Lia M. | |
Caspers, Laure E. | |
Vidović Valentinčič, Nataša | 20708 |
Štunf, Špela | 31505 |
Groot-Mijnes, Jolanda D.F. de | |
Rothova, Aniki |
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